Caution is recommended if paracetamol is administered concomitantly with flucloxacillin as a result of amplified possibility of high anion gap metabolic acidosis (HAGMA), specifically in patients with severe renal impairment, sepsis, malnutrition and other sources of glutathione deficiency (e.
• Don't take for longer than directed by your prescriber as taking dihydrocodeine on a regular basis for any long time can cause addiction.
Concomitant use of Dihydrocodeine tablets and sedative medicines for example benzodiazepines or connected drugs boosts the threat of drowsiness, challenges in respiration (respiratory depression), coma and may be lifethreatening.
AA. Characterization on the human cytochrome P450 enzymes associated with the metabolism of dihydrocodeine.
Drug withdrawal syndrome could occur on abrupt cessation of therapy or dose reduction. When a patient no longer calls for therapy, it is highly recommended to taper the dose step by step to minimise symptoms of withdrawal. Tapering from the high dose may take months to months.
Reporting of adverse reactions Reporting suspected adverse reactions just after authorisation with the medicinal product is important. It permits ongoing checking of your profit/chance balance on the medicinal product.
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indications of an allergic reaction like itchy pores and skin rash, swelling from the encounter, lips, tongue or throat, or difficulty respiration or swallowing
Crucial: Medicine safety Tell your doctor or pharmacist if you take any other medicines, which include herbal therapies, natural vitamins or dietary supplements.
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Gastric contents might therefore must be emptied, as this can be handy in eradicating unabsorbed drug, especially when a prolonged launch formulation has been taken.
Get medical help without delay in the event you have any quite really serious side effects, together with: fainting, seizure.
To decrease your danger, your health care provider really should have you take the smallest dose of dihydrocodeine that works, and take it to the shortest feasible time. See also How you can Use section for more information read more about addiction.
If you have been given dihydrocodeine liquid medicine for your child, check the label carefully to make positive you happen to be offering the right dose.